The use of gene expression trajectories to predict neurodegeneration

Takeaway

  • The gene expression contrastive trajectory interference (GE-cTI) is a promising tool for the prediction of disease progression and clinical deterioration in people with neurodegenerative disease.

Why this matters ?

  • There is a lack of longitudinal data assessing the progressive course of neurodegenerative disease.

  • Better understanding the temporal evolution of disease could have practical implications for the development of personalized strategies in these patients.