The clinical relevance of RNF213 p.R4810K in Chinese people with moyamoya disease

Takeaway

  • Homozygosity and heterozygosity of ring finger protein 213 (RNF213) p.R4810K can predict posterior cerebral artery (PCA) involvement and early onset of disease in Chinese people with moyamoya disease (MMD).

Why this matters

    The clinical relevance of RNF213 p.R4810K genotype has not been previously assessed in the Chinese population.