rs2651899 polymorphism of the PRDM16 gene increases risk of common migraine subtypes

Takeaway

  • PRDM16 rs2651899 polymorphism is significantly associated with the risk of developing two common migraine subtypes, migraine with aura (MA) and migraine without aura (MO).

Why this matters

    PRDM16 may represent a potential therapeutic target in migraine. Larger studies with functional variations of PRDM16 will help to elucidate its biological role in the development of migraines.