Right lingual/fusiform gyrus dysfunction affects semantic deficit in amyotrophic lateral sclerosis

Takeaway

  • In neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), clinical symptoms are not solely derived from one lesion, but from network impairment.

Why this matters

    Neuropsychological symptoms should be considered as network-based impairments to better understand cognitive deficit in ALS.