Logopenic variant primary progressive aphasia with dyslexia linked to aberrant cortical development

Takeaway

  • Pathological developmental and neurodegenerative changes are both present in the language network of people with logopenic variant primary progressive aphasia.

Why this matters

    Neurodevelopmental changes in early life could affect predisposition to neurodegenerative disease in later life, and play a role in non-amnestic, early age of onset presentations of Alzheimer’s disease.