Investigating safety outcomes with early mobilization of stroke patients


  • Very early mobilization of stroke patients is associated with increased risk of mortality 14-days post-stroke.

Why this matters

  • It is unclear as to the risk-benefit profile of early mobilization following stroke.

  • A Very Early Rehabilitation Trial (AVERT) was a randomized trial which investigated the difference in serious adverse event (SAE) outcomes between a very early mobilization protocol (VEM) which included a higher amount, frequency and intensity of out-of-bed, task-specific training of sitting, standing and walking as compared to usual standard of care (UC).

  • The primary safety endpoints for AVERT were read-out at 3 months post-stroke; however, a prespecified analysis was also planned for a 14-day analysis, the results of which are reported here.

International Medical Press is a global provider of independent medical education. Its mission is to provide healthcare professionals with high-quality, trusted medical information with the aim of helping optimize patient care.

No responsibility is assumed by International Medical Press for any injury and/or damage to persons or property through negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. Because of rapid advances in the medical sciences, International Medical Press recommends that independent verification of diagnoses and drug dosages should be made. The opinions expressed do not reflect those of International Medical Press or the sponsor. International Medical Press assumes no liability for any material contained herein.