Instrumentally-assessed gait quality is linked to self-reported walking ability in early-stage multiple sclerosis

Takeaway

  • Using inertial sensors to measure gait velocity and quality in people with multiple sclerosis can provide sensitive biomarkers to detect even minor impairments in the early stages of the disease.

Why this matters ?

  • People with multiple sclerosis often report limited walking ability despite the gold-standard Expanded Disability Status Scale indicating normal walking autonomy.

  • These important findings suggest that instrumentally-assessed gait quality aspects may be sensitive enough biomarkers to detect subtle impairments even in the earliest stages of the multiple sclerosis.