Increased 11C-PBB3 binding can be observed in patients suffering from traumatic brain injury

Takeaway

  • Increased 11C-PBB3 binding is associated with late-onset neuropsychiatric symptoms in patients suffering from traumatic brain injury (TBI), in particular for patient with psychosis.

Why this matters

    The association of the spatio-temporal arrangement of tau abnormalities and clinical manifestations has not been studied in long-term survivors of TBI.