Characterizing the clinical course of relapse in neuromyelitis optica spectrum disorder

Takeaway

  • Individuals with neuromyelitis optica spectrum disorder (NMOSD) demonstrated a mixed clinical course which involved a “clustered” period and a “nonclustered” intermittent period of clinical attacks.

Why this matters

    Suppressing relapses in NMOSD is crucial for disease management, however, there is little research on the relapse timing and sequential patterns of clinical attack occurrence. Results from this study suggest that clinicians should focus on the clinical course of the individual when deciding on a relapse-prevention strategy.