Certain non-motor symptoms are linked to Parkinson’s disease progression

Takeaway

  • Newly diagnosed Parkinson’s disease (PD) individuals exhibit certain non-motor features (REM disorders, memory impairment, etc.) that correlate with deficits in nigrostriatal dopamine binding.

Why this matters

    Non-motor symptoms (NMS) may indicate PD pathology before diagnosis and can serve as biomarkers of PD progression.