Alzheimer’s disease risk and APOE in Caribbean Hispanics

Takeaway

  • The effect of APOE E2/E3/E4 genotypes on Alzheimer’s disease (AD) risk differs between Caribbean Hispanic and European data sets and are influenced by local ancestry.

Why this matters ?

    Genetic risk in AD in diverse populations is not well understood; these data facilitate greater understanding of individual-level risks and the pathogenesis of AD across diverse populations.